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Acoustic Neuroma – Clinical Trials and Research Studies

Genetic disorder in NF2 is considered a major cause for acoustic neuroma. Although 1 in 25,000 people may have NF2, yet not all develop acoustic neuroma. Operative mortality rate for acoustic neuroma is less than 1%, although this was much higher earlier.

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Clinical Trials and Research Studies on Acoustic Neuroma

New York (USA), June 19, 2013

Acoustic Neuroma: Clinical Trials and Research Studies

Genetic disorder in NF2 is considered a major cause for acoustic neuroma. Although 1 in 25,000 people may have NF2, yet not all develop acoustic neuroma. It affects only 2 people in 100,000 people in a year. Most patients are within the age of thirty and sixty. In rare cases, teenagers and young adults develop acoustic neuroma.

Normally, acoustic neuroma in an adult may present as a tumor developing on a nerve. It starts from the eighth cranial nerve on the vestibular portion from inside auditory canal. As it grows, it starts compressing fifth, seventh and sometimes the ninth and tenth cranial nerves. This leads to increased intracranial pressure and obstruction of cerebrospinal fluid flow.

Acoustic neuromas can be unilateral or bilateral. Neuromas due to NF2 are bilateral and occur because of genetic defects. However, it is not clear as to what causes unilateral tumors occurring due to defects in chromosome 22. There is no conclusive evidence about gene malfunctioning.

Operative mortality rate for acoustic neuroma is presently less than one percent, although this was much higher earlier. Acoustic surgery no longer causes facial paralysis. Hearing abilities also improve considerably after proper treatment of acoustic neuroma.

Early diagnosis of acoustic neuroma is now possible through improved imaging techniques, development of facial and auditory nerve monitoring techniques, adaptation of microscope to operating theater, and better operative management procedures.

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