Causes and Evaluation of Agnogenic Myeloid Metaplasia - What causes an Agnogenic Myeloid Metaplasia? What are common causes of Agnogenic Myeloid Metaplasia? What are the practice parameters for evaluation of Agnogenic Myeloid Metaplasia?
Causes and Evaluation of Agnogenic Myeloid Metaplasia
New York (USA), November 29, 2014
What causes an Agnogenic Myeloid Metaplasia?
What are the most common causes of Agnogenic Myeloid Metaplasia?
How is an Agnogenic Myeloid Metaplasia usually evaluated?
What are the practice parameters for the evaluation of Agnogenic Myeloid Metaplasia?
What are the practice guidelines for the evaluation of Agnogenic Myeloid Metaplasia clinically?
What issues are most important in the initial evaluation Agnogenic Myeloid Metaplasia?
Learn more about the causes and evaluation of Agnogenic Myeloid Metaplasia.
Agnogenic Myeloid Metaplasia – Causes and Evaluation
Causes of Agnogenic Myeloid Metaplasia
There is no concrete and definitive cause of Agnogenic Myeloid Metaplasia. Recent research indicates DNA mutations could be responsible for AMM. A specific mutation, JAK2V617F, is normally found in people with AMM. This mutation in JAK2 gene deregulates pathway signaling within your cells. As a result, your body now produces the wrong number of blood cells.
Other possible causes include:
– Mutations of other proteins in other pathways
– Deregulation of JAK pathway signaling
– Deregulation of mTOR and Ras pathways
– Gene activation
– Presence of leukemia and lymphoma
Evaluation of Agnogenic Myeloid Metaplasia
Your bones contain bone marrow, a soft fatty tissue. It consists of various immature stem cells. These produce blood cells. Your blood consists of red blood cells, white blood cells, and platelets. Red blood cells carry oxygen to different body parts, white blood cells fight infection, and platelets help in clotting of blood.
When genetic mutations scar bone marrow, production of blood cells is severely affected. This causes infections, bleeding, anemia, and other problems. Sometimes your liver or spleen may enlarge while trying to make blood cells. This is extramedullary hematopoiesis.
The reason behind genetic mutations is unknown. Mutated blood stem cells duplicate and divide. Mutations continue to occur in these new cells. As number of mutated cells increase, blood production in your body is disrupted. Your white blood cell count increases excessively and platelet count fluctuates.
Agnogenic Myeloid Metaplasia – Definition and Diagnosis
Definition and Diagnosis of Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Signs and Symptoms
Signs and Symptoms of Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Complications and Risk Factors
Complications and Risk Factors for Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Diagnostic Tests and Procedures
Diagnostic Tests and Procedures for Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Treatments and Medications
Treatments and Medications for Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Clinical Trials and Research Studies
Clinical Trials and Research Studies on Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Home Remedies and Alternative Therapies
Home Remedies and Alternative Therapies for Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Prevention and Coping
Prevention and Coping with Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Lifestyle Changes and Self-Help
Lifestyle Changes and Self-Help for Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasia – Prevention, Treatment, and Remedies
Agnogenic Myeloid Metaplasia – Causes, Symptoms, Diagnosis, Prevention, Treatment, and Remedies